Tagara or Valeriana wallichi root stocks are aromatic; they yield aromatic oil, which contains valeric acid. Tagara has a relaxing effect on the body and is used in treating insomnia and sleep disorders.
Active constituents:
The roots and rhizomes are highly aromatic and contain valepotriates and essential oils. In addition, sesquiterpenoids, monoterpenoids, lignans and alkaloids with pharmacological properties have been found in Tagara. Hesperidin and methylapigenin present in Tagara are found to have sedative and sleep enhancing properties. Valerenic acid present in the herb has been shown to inhibit the enzyme-induced breakdown of gamma-aminobutyric acid (GABA), the brain's chief inhibitory neurotransmitter. This action results in sedation.
Functions:
Insomnia: The sedative action of Tagara mildly depresses the central nervous system, which is beneficial in sleep disorders like insomnia.Six-methylapigenin, which is an active compound of Tagara, acts as a benzodiazepine-binding site (BDZ-bs) ligand. This action enhances the inhibitory effects of GABA, leading to the complete blockage of the ongoing nerve impulse and sedation.
Nervine disorders: Tagara maintains normal nervine function and is also used in treating anxiety and tremors. It relieves nervous irritation and agitation. In studies, extracts of Tagaramarkedly attenuated cerebral injury in terms of decreased brain infarct (an area of dead tissue due to lack of oxygen) size, and an increase in short-term memory and motor coordination.
Antidepressant and anxiolytic action: Tagara extract is useful in the treatment of human stress-related disorders. It significantly reduces stress and anxiety, relieves depression, and enhances the willingness to adjust without altering memory, concentration or attention.
Indications:
Insonmia
Sleep disorders
Recommended dose:
One capsule, twice a day after meals.
Composition:
Each capsule contains 250mg extract of Tagara.